Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue. Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking. A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.
Is there any treatment?
Anyone with signs of moderate or severe TBI should receive medical attention as soon as possible. Because little can be done to reverse the initial brain damage caused by trauma, medical personnel try to stabilize an individual with TBI and focus on preventing further injury. Primary concerns include insuring proper oxygen supply to the brain and the rest of the body, maintaining adequate blood flow, and controlling blood pressure. Imaging tests help in determining the diagnosis and prognosis of a TBI patient. Patients with mild to moderate injuries may receive skull and neck X-rays to check for bone fractures or spinal instability. For moderate to severe cases, the imaging test is a computed tomography (CT) scan. Moderately to severely injured patients receive rehabilitation that involves individually tailored treatment programs in the areas of physical therapy, occupational therapy, speech/language therapy, physiatry (physical medicine), psychology/psychiatry, and social support.
What is the prognosis?
Approximately half of severely head-injured patients will need surgery to remove or repair hematomas (ruptured blood vessels) or contusions (bruised brain tissue). Disabilities resulting from a TBI depend upon the severity of the injury, the location of the injury, and the age and general health of the individual. Some common disabilities include problems with cognition (thinking, memory, and reasoning), sensory processing (sight, hearing, touch, taste, and smell), communication (expression and understanding), and behavior or mental health (depression, anxiety, personality changes, aggression, acting out, and social inappropriateness). More serious head injuries may result in stupor, an unresponsive state, but one in which an individual can be aroused briefly by a strong stimulus, such as sharp pain; coma, a state in which an individual is totally unconscious, unresponsive, unaware, and unarousable; vegetative state, in which an individual is unconscious and unaware of his or her surroundings, but continues to have a sleep-wake cycle and periods of alertness; and a persistent vegetative state (PVS), in which an individual stays in a vegetative state for more than a month.
What research is being done?
The National Institute of Neurological Disorders and Stroke (NINDS) conducts TBI research in its laboratories at the National Institutes of Health (NIH) and also supports TBI research through grants to major medical institutions across the country. This research involves studies in the laboratory and in clinical settings to better understand TBI and the biological mechanisms underlying damage to the brain. This research will allow scientists to develop strategies and interventions to limit the primary and secondary brain damage that occurs within days of a head trauma, and to devise therapies to treat brain injury and improve long-term recovery of function.
More information about Traumatic Brain Injury (TBI) Research is available at: http://www.ninds.nih.gov/research/tbi/index.htm
NIH Patient Recruitment for Traumatic Brain Injury Clinical Trials
- At NIH Clinical Center
- Throughout the U.S. and Worldwide
- NINDS Clinical Research Collaboration Trials
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Acoustic Neuroma Association 600 Peachtree Parkway Suite 108 Cumming, GA 30041 info@anausa.org http://www.anausa.org Tel: 770-205-8211 877-200-8211 Fax: 770-205-0239/877-202-0239 |
Brain Injury Association of America, Inc. 1608 Spring Hill Rd Suite 110 Vienna, VA 22182 braininjuryinfo@biausa.org http://www.biausa.org Tel: 703-761-0750 800-444-6443 Fax: 703-761-0755 |
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Brain Trauma Foundation 7 World Trade Center 250 Greenwich Street 34th Floor New York, NY 10017 education@braintrauma.org http://www.braintrauma.org Tel: 212-772-0608 Fax: 212-772-0357 |
Family Caregiver Alliance/ National Center on Caregiving 180 Montgomery Street Suite 900 San Francisco, CA 94104 info@caregiver.org http://www.caregiver.org Tel: 415-434-3388 800-445-8106 Fax: 415-434-3508 |
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National Rehabilitation Information Center (NARIC) 8201 Corporate Drive Suite 600 Landover, MD 20785 naricinfo@heitechservices.com http://www.naric.com Tel: 301-459-5900/301-459-5984 (TTY) 800-346-2742 Fax: 301-562-2401 |
National Stroke Association 9707 East Easter Lane Suite B Centennial, CO 80112-3747 info@stroke.org http://www.stroke.org Tel: 303-649-9299 800-STROKES (787-6537) Fax: 303-649-1328 |
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National Institute on Disability and Rehabilitation Research (NIDRR) U.S. Department of Education Office of Special Education and Rehabilitative Services 400 Maryland Ave., S.W. Washington, DC 20202-7100 http://www.ed.gov/about/offices/list/osers/nidrr Tel: 202-245-7460 202-245-7316 (TTY) |
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Traumatic Brain Injury: Hope Through Research
A booklet about traumatic brain injury (TBI), or head injury, prepared by the National Institute of Neurological Disorders and Stroke (NINDS). -
Clinical Trials in Head Injury
Summary of a workshop, Clinical Trials in Head Injury, held May 12 and 13, 2000 -
NINDS Shaken Baby Syndrome Information Page
Shaken baby syndrome information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). -
Traumatic Brain Injury (TBI) Research
Research and contact information related to Traumatic Brain Injury (TBI) at NINDS
Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892
NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.
